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Investigators from multiple institutions conducted a systematic review and meta-analysis to determine the susceptibility to, and transmission of, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents compared to adults. Investigators searched PubMed and the medical preprint server medRxiv for articles published through July 28, 2020. Studies that provided data on proven SARS-CoV-2 infection and reported either rate of secondary infections in children and adolescents compared to adults (contact-tracing studies) or infection prevalence or seroprevalence in children and adolescents separate from adults (prevalence studies) were included. Studies that reported single-institution outbreaks or only included children were excluded.
Identified studies were reviewed for eligibility by 2 investigators. Methodological …
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