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Investigators from Boston Children’s Hospital, Boston, MA, conducted a retrospective study to describe the distribution of pathogenic bacteria among children <2 years old with a urinary tract infection (UTI) who have a nitrite-negative urinalysis. Specifically, the investigators sought to determine the prevalence of enterococcus in young children with a nitrite-negative urinalysis to evaluate whether empiric antibiotics should be adjusted in a patient <2 years old being treated for possible UTI. For the study, they identified children <2 years old seen in a single academic pediatric emergency department between 2009 and 2014 who had urine obtained by catherization and had paired urine culture and urinalysis results. Patients were classified as having a UTI if their urine …
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