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Urinary protein excretion and glomerular permeability to proteins as measured by urinary protein electrophoresis was assessed in 13 children with steroid-resistant nephrotic syndrome (SRNS) (10 boys, ages 1.8 to 12 years) in Santiago, Chile. Biopsy diagnoses included focal segmented glomerular sclerosis (4), membranoproliferative glomerular nephritis type 1 (3), crescentic glomerulonephritis (3), minimal change nephrotic syndrome with IgM deposits (2), and diffuse mesangial sclerosis (1). All children initially received oral prednisone 60 mg/M2 daily for 8 weeks, 8 also …
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