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American Academy of Pediatrics
HEMATOLOGY-ONCOLOGY

Late Mortality in Childhood Cancer: Time to Count Our Chips

AAP Grand Rounds October 2001, 6 (4) 40-41; DOI: https://doi.org/10.1542/gr.6-4-40
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Sources: (1) Mertens AC,Yasui Y, Neglia JP, et al. Late mortality experience in five-year survivors of childhood and adolescent cancer: the Childhood Cancer Survivor Study. Clin Oncol. 2001;19:3163–3172.OpenUrl (2) Möller TR, Garwicz S, Barlow L, et al. Decreasing late mortality among five-year survivors of cancer in childhood and adolescence: a population-based study in the Nordic countries. J Clin Oncol. 2001;19:3173–3181.OpenUrlAbstract/FREE Full Text

Survivors of childhood and adolescent cancer remain at risk for a shortened life span because of the possible long-term sequelae of cancer therapy and recurrence of the primary malignancy. These 2 excellent reports, a multi-institutional study from The Childhood Cancer Survivor Study (CCSS) in the US, and a population-based study in 5 Nordic countries (Denmark, Finland, Iceland, Norway, and Sweden), are the largest studies to date evaluating long-term survivors of childhood cancer. The purpose of both retrospective studies was to assess the risk of death among childhood and adolescent cancer survivors.

The CCSS was a retrospectivecohort study initiated in 1994 and designed to study late effects among long-term survivors of childhood cancer. The study population consisted of a cohort of 20,227 patients who were less than 21 years of age when diagnosed with cancer between 1970 and 1986 and who survived at least 5 years beyond the date of diagnosis. Standardized mortality ratios (SMRs) were calculated based on 208,947 person-years of follow-up in …

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AAP Grand Rounds: 6 (4)
AAP Grand Rounds
Vol. 6, Issue 4
1 Oct 2001
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Late Mortality in Childhood Cancer: Time to Count Our Chips
AAP Grand Rounds Oct 2001, 6 (4) 40-41; DOI: 10.1542/gr.6-4-40

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Late Mortality in Childhood Cancer: Time to Count Our Chips
AAP Grand Rounds Oct 2001, 6 (4) 40-41; DOI: 10.1542/gr.6-4-40
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